Khwaish is based on the life of Afreen, who lives with her family in Dubai. Afreen is married to Kabir, and soon after her wedding, gets pregnant and is expecting her first child. Everything is going great, when tragedy strikes and Kabir passes away in an accident. Circumstances lead Afreen to marry her brother-in-law (Kabir's younger brother) Azaan, who has never got along with her. Misunderstandings start affecting all the relationships in the family. However, with time, Azaan and Afreen start liking each other. And then one day, they see a man who is exactly like Kabir. Is this his look-alike or had he survived the accident? Was the accident staged by someone close to them? And who should now be considered Afreen's husband?